| # | District | Region | Type | Population (2021 census) | Against the highest | vs median |
|---|---|---|---|---|---|---|
| 1 | Kumasi Metropolitan | Ashanti | metropolitan | 444k | +338% | |
| 2 | Kpone Katamanso | Greater Accra | municipal | 417k | +312% | |
| 3 | Tamale Metropolitan | Northern | metropolitan | 375k | +270% | |
| 4 | Ga South Municipal | Greater Accra | municipal | 350k | +246% | |
| 5 | Sagnerigu | Northern | municipal | 342k | +237% | |
| 6 | Ga Central Municipal | Greater Accra | municipal | 332k | +228% | |
| 7 | Ga West Municipal | Greater Accra | municipal | 314k | +210% | |
| 8 | Gomoa East | Central | district | 309k | +205% | |
| 9 | Kwabre East | Ashanti | municipal | 297k | +193% | |
| 10 | Accra Metropolis | Greater Accra | metropolitan | 284k | +181% | |
| 11 | Ga East | Greater Accra | municipal | 283k | +180% | |
| 12 | Ketu South | Volta | municipal | 253k | +150% | |
| 13 | Sekondi Takoradi Metropolis | Western | metropolitan | 245k | +142% | |
| 14 | La-Nkwantanang-Madina | Greater Accra | municipal | 245k | +142% | |
| 15 | Techiman Municipal | Bono East | municipal | 243k | +140% | |
| 16 | Adenta Municipal | Greater Accra | municipal | 238k | +135% | |
| 17 | Awutu Senya East | Central | municipal | 237k | +134% | |
| 18 | Ga North Municipal | Greater Accra | municipal | 235k | +132% | |
| 19 | Atwima Kwanwoma | Ashanti | district | 235k | +132% | |
| 20 | Afigya Kwabre South | Ashanti | district | 235k | +132% | |
| 21 | Prestea/Huni Valley | Western | municipal | 229k | +126% | |
| 22 | Tarkwa Nsuaem | Western | municipal | 219k | +116% | |
| 23 | Ledzokuku Municipal | Greater Accra | municipal | 217k | +115% | |
| 24 | Weija Gbawe Municipal | Greater Accra | municipal | 214k | +111% | |
| 25 | Oforikrom Municipal | Ashanti | municipal | 213k | +110% | |
| 26 | Ashaiman Municipal | Greater Accra | municipal | 208k | +105% | |
| 27 | Ningo/Prampram | Greater Accra | district | 205k | +102% | |
| 28 | Wa Municipal | Upper West | municipal | 201k | +98% | |
| 29 | Tema West Municipal | Greater Accra | municipal | 196k | +94% | |
| 30 | Sunyani Municipal | Bono | municipal | 194k | +91% | |
| 31 | Asokore Mampong Municipal | Ashanti | municipal | 191k | +89% | |
| 32 | Cape Coast Metropolitan | Central | metropolitan | 190k | +88% | |
| 33 | Nanumba North | Northern | municipal | 189k | +86% | |
| 34 | East Mamprusi | North East | municipal | 188k | +86% | |
| 35 | Ejisu Municipal | Ashanti | municipal | 181k | +78% | |
| 36 | Ho Municipal | Volta | municipal | 180k | +78% | |
| 37 | Wassa Amenfi East | Western | municipal | 180k | +77% | |
| 38 | Tema Metropolitan | Greater Accra | metropolitan | 178k | +76% | |
| 39 | West Mamprusi Municipal | North East | municipal | 176k | +74% | |
| 40 | Effia Kwesimintsim Municipal | Western | municipal | 174k | +72% | |
| 41 | Ablekuma Central Municipal | Greater Accra | municipal | 169k | +67% | |
| 42 | Mfantseman Municipal | Central | municipal | 169k | +67% | |
| 43 | Bibiani-Anhwiaso-Bekwai Municipal | Western North | municipal | 168k | +66% | |
| 44 | Komenda-Edina-Eguafo-Abirem Municipal | Central | municipal | 166k | +64% | |
| 45 | Bosomtwe | Ashanti | district | 165k | +63% | |
| 46 | Atwima Nwabiagya South | Ashanti | municipal | 162k | +60% | |
| 47 | Awutu Senya | Central | district | 161k | +59% | |
| 48 | Okaikwei North Municipal | Greater Accra | municipal | 160k | +58% | |
| 49 | Ablekuma North Municipal | Greater Accra | municipal | 159k | +57% | |
| 50 | Nsawam Adoagyiri | Eastern | municipal | 156k | +54% | |
| 51 | Atwima Mponua | Ashanti | district | 155k | +53% | |
| 52 | Atwima Nwabiagya North | Ashanti | district | 155k | +53% | |
| 53 | Kwadaso Municipal | Ashanti | municipal | 155k | +53% | |
| 54 | Yendi Municipal | Northern | municipal | 154k | +53% | |
| 55 | Gushegu | Northern | municipal | 154k | +52% | |
| 56 | Ablekuma West Municipal | Greater Accra | municipal | 153k | +52% | |
| 57 | Ahanta West Municipal | Western | municipal | 153k | +51% | |
| 58 | Sefwi-Wiawso | Western North | municipal | 151k | +49% | |
| 59 | Asunafo North Municipal | Ahafo | municipal | 150k | +48% | |
| 60 | Kwahu West | Eastern | municipal | 145k | +44% | |
| 61 | Atebubu Amantin | Bono East | municipal | 145k | +43% | |
| 62 | Bawku West | Upper East | district | 144k | +42% | |
| 63 | Krowor Municipal | Greater Accra | municipal | 143k | +41% | |
| 64 | Central Gonja | Savannah | district | 143k | +41% | |
| 65 | La Dade-Kotopon | Greater Accra | municipal | 140k | +39% | |
| 66 | Bolgatanga Municipal | Upper East | municipal | 140k | +38% | |
| 67 | Kintampo North Municipal | Bono East | municipal | 140k | +38% | |
| 68 | Bekwai Municipal | Ashanti | municipal | 138k | +36% | |
| 69 | Ejura-Sekyedumase | Ashanti | municipal | 138k | +36% | |
| 70 | Offinso Municipal | Ashanti | municipal | 137k | +36% | |
| 71 | Agona West Municipal | Central | municipal | 137k | +35% | |
| 72 | Suame Municipal | Ashanti | municipal | 136k | +35% | |
| 73 | Sunyani West | Bono | district | 136k | +34% | |
| 74 | Nkwanta South Municipal | Oti | municipal | 136k | +34% | |
| 75 | Wassa Amenfi West | Western | municipal | 130k | +28% | |
| 76 | Aowin | Western North | municipal | 130k | +28% | |
| 77 | Gomoa West | Central | district | 130k | +28% | |
| 78 | Asikuma-Odoben-Brakwa | Central | district | 127k | +25% | |
| 79 | Jomoro | Western | municipal | 127k | +25% | |
| 80 | Suhum Municipal | Eastern | municipal | 126k | +25% | |
| 81 | Kpandai | Northern | district | 126k | +25% | |
| 82 | Nkwanta North | Oti | district | 126k | +25% | |
| 83 | Asokwa Municipal | Ashanti | municipal | 126k | +24% | |
| 84 | New Juaben South Municipal | Eastern | municipal | 125k | +24% | |
| 85 | Wenchi Municipal | Bono | municipal | 125k | +23% | |
| 86 | Abura-Asebu-Kwamankese | Central | district | 124k | +23% | |
| 87 | Asante Akim South | Ashanti | municipal | 124k | +22% | |
| 88 | Savelugu | Northern | municipal | 123k | +21% | |
| 89 | Yilo Krobo | Eastern | municipal | 123k | +21% | |
| 90 | Kwaebibirem | Eastern | municipal | 122k | +20% | |
| 91 | Lower Manya | Eastern | municipal | 121k | +20% | |
| 92 | Ellembelle | Western | district | 121k | +19% | |
| 93 | Ajumako-Enyan-Essiam | Central | district | 121k | +19% | |
| 94 | Bongo | Upper East | district | 120k | +19% | |
| 95 | West Akim | Eastern | municipal | 120k | +19% | |
| 96 | Sekyere South | Ashanti | district | 120k | +19% | |
| 97 | Bawku Municipal | Upper East | municipal | 119k | +18% | |
| 98 | Wassa Amenfi Central | Western | district | 119k | +18% | |
| 99 | Tolon | Northern | district | 118k | +17% | |
| 100 | Jaman North | Bono | district | 118k | +16% | |
| 101 | East Gonja Municipal | Savannah | municipal | 118k | +16% | |
| 102 | Shama | Western | district | 117k | +16% | |
| 103 | Mampong Municipal | Ashanti | municipal | 117k | +15% | |
| 104 | Amansie South | Ashanti | district | 116k | +15% | |
| 105 | Bia West | Western North | district | 116k | +14% | |
| 106 | Bole | Savannah | district | 116k | +14% | |
| 107 | Tain | Bono | district | 116k | +14% | |
| 108 | Ketu North | Volta | municipal | 115k | +13% | |
| 109 | Nkoranza South | Bono East | municipal | 115k | +13% | |
| 110 | Hohoe Municipal | Volta | municipal | 114k | +13% | |
| 111 | Old Tafo Municipal | Ashanti | municipal | 114k | +13% | |
| 112 | Karaga | Northern | district | 114k | +13% | |
| 113 | South Tongu | Volta | district | 113k | +12% | |
| 114 | Dormaa Municipal | Bono | municipal | 113k | +11% | |
| 115 | Sawla-Tuna-Kalba | Savannah | district | 113k | +11% | |
| 116 | North Tongu | Volta | district | 111k | +10% | |
| 117 | Kumbungu | Northern | district | 111k | +9% | |
| 118 | Krachi East Municipal | Oti | municipal | 110k | +9% | |
| 119 | Upper Denkyira East Municipal | Central | municipal | 110k | +9% | |
| 120 | Amansie West | Ashanti | district | 109k | +8% | |
| 121 | Jaman South Municipal | Bono | municipal | 108k | +7% | |
| 122 | Effutu Municipal | Central | municipal | 108k | +6% | |
| 123 | Nanumba South | Northern | district | 106k | +5% | |
| 124 | Berekum East Municipal | Bono | municipal | 106k | +5% | |
| 125 | Assin South | Central | district | 106k | +5% | |
| 126 | Shai Osudoku | Greater Accra | district | 106k | +4% | |
| 127 | Akwapem North | Eastern | municipal | 105k | +4% | |
| 128 | Obuasi Municipal | Ashanti | municipal | 104k | +3% | |
| 129 | Techiman North | Bono East | district | 103k | ≈ | |
| 130 | Pru East | Bono East | district | 102k | ≈ | |
| 131 | Asuogyaman | Eastern | district | 101k | ≈ | |
| 132 | Twifo Atti-Morkwa | Central | district | 101k | ≈ | |
| 133 | Kasena Nankana East | Upper East | municipal | 100k | ≈ | |
| 134 | Wassa East | Western | district | 100k | ≈ | |
| 135 | Agona East | Central | district | 98k | −3% | |
| 136 | Wa West | Upper West | district | 97k | −4% | |
| 137 | Saboba | Northern | district | 96k | −6% | |
| 138 | Mion | Northern | district | 95k | −6% | |
| 139 | Anloga | Volta | district | 95k | −6% | |
| 140 | Ayawaso Central Municipal | Greater Accra | municipal | 95k | −6% | |
| 141 | Nzema East | Western | municipal | 95k | −7% | |
| 142 | Ayensuano | Eastern | district | 95k | −7% | |
| 143 | Tano North Municipal | Ahafo | municipal | 94k | −8% | |
| 144 | Upper West Akim | Eastern | district | 93k | −8% | |
| 145 | New Juaben North Municipal | Eastern | municipal | 93k | −8% | |
| 146 | Amansie Central | Ashanti | district | 93k | −8% | |
| 147 | Ahafo Ano North | Ashanti | municipal | 93k | −8% | |
| 148 | Akatsi South | Volta | district | 92k | −9% | |
| 149 | Obuasi East | Ashanti | district | 92k | −9% | |
| 150 | Asunafo South | Ahafo | district | 92k | −9% | |
| 151 | Asante Akim Central Municipal | Ashanti | municipal | 92k | −9% | |
| 152 | Wa East | Upper West | district | 91k | −10% | |
| 153 | Abuakwa North | Eastern | municipal | 91k | −10% | |
| 154 | Jirapa | Upper West | municipal | 91k | −10% | |
| 155 | Akyem Mansa | Eastern | district | 91k | −10% | |
| 156 | Upper Denkyira West | Central | district | 91k | −10% | |
| 157 | Kasena Nankana West | Upper East | district | 91k | −10% | |
| 158 | Kintampo South | Bono East | district | 89k | −12% | |
| 159 | Juaboso | Western North | district | 89k | −12% | |
| 160 | Assin Fosu | Central | municipal | 89k | −12% | |
| 161 | Tano South Municipal | Ahafo | municipal | 87k | −14% | |
| 162 | Chereponi | North East | district | 87k | −14% | |
| 163 | Talensi | Upper East | district | 87k | −14% | |
| 164 | Tempane | Upper East | district | 87k | −14% | |
| 165 | Asante Akim North | Ashanti | district | 86k | −15% | |
| 166 | Adansi South | Ashanti | district | 85k | −16% | |
| 167 | Central Tongu | Volta | district | 84k | −17% | |
| 168 | Gomoa Central | Central | district | 84k | −17% | |
| 169 | Offinso North | Ashanti | district | 83k | −18% | |
| 170 | Ho West | Volta | district | 83k | −18% | |
| 171 | Zabzugu | Northern | district | 83k | −18% | |
| 172 | Birim North | Eastern | district | 83k | −18% | |
| 173 | Bunkpurugu Nakpanduri | North East | district | 82k | −19% | |
| 174 | Sissala East | Upper West | municipal | 81k | −20% | |
| 175 | Assin North | Central | district | 81k | −20% | |
| 176 | Pusiga | Upper East | district | 81k | −20% | |
| 177 | Kwahu South | Eastern | district | 80k | −21% | |
| 178 | Krachi Nchumuru | Oti | district | 80k | −21% | |
| 179 | Kwahu East | Eastern | district | 80k | −21% | |
| 180 | Keta Municipal | Volta | municipal | 79k | −22% | |
| 181 | Asene Akroso Manso | Eastern | district | 77k | −23% | |
| 182 | Nadowli-Kaleo | Upper West | district | 77k | −24% | |
| 183 | Denkyembour | Eastern | district | 77k | −24% | |
| 184 | Akwapem South | Eastern | district | 77k | −24% | |
| 185 | Binduri | Upper East | district | 77k | −24% | |
| 186 | Ada East | Greater Accra | district | 76k | −25% | |
| 187 | Birim Central Municipal | Eastern | municipal | 76k | −25% | |
| 188 | Ada West | Greater Accra | district | 76k | −25% | |
| 189 | Ayawaso West | Greater Accra | municipal | 75k | −26% | |
| 190 | Tatale Sanguli | Northern | district | 75k | −26% | |
| 191 | Sekyere East | Ashanti | district | 75k | −26% | |
| 192 | Kwahu Afram Plains South | Eastern | district | 74k | −27% | |
| 193 | Kadjebi | Oti | district | 74k | −27% | |
| 194 | Abuakwa South | Eastern | municipal | 74k | −27% | |
| 195 | Asutifi North | Ahafo | district | 74k | −27% | |
| 196 | Afigya Kwabre North | Ashanti | district | 73k | −28% | |
| 197 | Sekyere Central | Ashanti | district | 73k | −28% | |
| 198 | Afadzato South | Volta | district | 73k | −28% | |
| 199 | Sene East | Bono East | district | 72k | −29% | |
| 200 | Adansi Asokwa | Ashanti | district | 72k | −29% | |
| 201 | Biakoye | Oti | district | 72k | −29% | |
| 202 | Garu | Upper East | district | 72k | −29% | |
| 203 | Upper Manya | Eastern | district | 71k | −30% | |
| 204 | Sefwi Akontombra | Western North | district | 70k | −31% | |
| 205 | Sene West | Bono East | district | 70k | −31% | |
| 206 | Pru West | Bono East | district | 69k | −31% | |
| 207 | Mamprugu Moagduri | North East | district | 69k | −32% | |
| 208 | Korle Klottey Municipal | Greater Accra | municipal | 69k | −32% | |
| 209 | Asutifi South | Ahafo | district | 68k | −32% | |
| 210 | Dormaa East | Bono | district | 68k | −33% | |
| 211 | Kwahu Afram Plains North | Eastern | district | 67k | −34% | |
| 212 | Twifo Hemang Lower Denkyira | Central | district | 66k | −35% | |
| 213 | Ahafo Ano South West | Ashanti | district | 66k | −35% | |
| 214 | Bodi | Western North | district | 66k | −35% | |
| 215 | Atiwa East | Eastern | district | 65k | −36% | |
| 216 | Sekyere Kumawu | Ashanti | district | 64k | −36% | |
| 217 | Juaben Municipal | Ashanti | municipal | 64k | −37% | |
| 218 | Sissala West | Upper West | district | 64k | −37% | |
| 219 | Ahafo Ano South East | Ashanti | district | 63k | −37% | |
| 220 | West Gonja | Savannah | district | 63k | −37% | |
| 221 | Ayawaso North Municipal | Greater Accra | municipal | 63k | −37% | |
| 222 | Bosome Freho | Ashanti | district | 62k | −39% | |
| 223 | North Gonja | Savannah | district | 61k | −39% | |
| 224 | Atiwa West | Eastern | district | 61k | −40% | |
| 225 | Krachi West | Oti | district | 61k | −40% | |
| 226 | Jasikan | Oti | district | 60k | −41% | |
| 227 | Kpando Municipal | Volta | municipal | 59k | −42% | |
| 228 | Lawra | Upper West | municipal | 58k | −42% | |
| 229 | South Dayi | Volta | district | 58k | −43% | |
| 230 | Fanteakwa North | Eastern | district | 57k | −44% | |
| 231 | Yunyoo-Nasuan | North East | district | 57k | −44% | |
| 232 | Ekumfi | Central | district | 57k | −44% | |
| 233 | Builsa North | Upper East | district | 57k | −44% | |
| 234 | Nkoranza North | Bono East | district | 56k | −44% | |
| 235 | Achiase | Eastern | district | 56k | −44% | |
| 236 | Fanteakwa South | Eastern | district | 55k | −46% | |
| 237 | Adansi North | Ashanti | district | 54k | −47% | |
| 238 | Bia East | Western North | district | 53k | −48% | |
| 239 | Ayawaso East Municipal | Greater Accra | municipal | 53k | −48% | |
| 240 | Mpohor | Western | district | 52k | −48% | |
| 241 | Nabdam | Upper East | district | 52k | −49% | |
| 242 | Okere | Eastern | district | 52k | −49% | |
| 243 | Nandom | Upper West | district | 51k | −49% | |
| 244 | Lambussie-Karni | Upper West | district | 51k | −50% | |
| 245 | Nanton | Northern | district | 51k | −50% | |
| 246 | Berekum West | Bono | district | 49k | −51% | |
| 247 | Adansi Akrofuom | Ashanti | district | 49k | −51% | |
| 248 | Dormaa West | Bono | district | 48k | −53% | |
| 249 | Agotime Ziope | Volta | district | 40k | −61% | |
| 250 | North East Gonja | Savannah | district | 39k | −61% | |
| 251 | North Dayi | Volta | district | 39k | −61% | |
| 252 | Bolga East | Upper East | district | 39k | −62% | |
| 253 | Daffiama Bussie Issa | Upper West | district | 39k | −62% | |
| 254 | Adaklu | Volta | district | 39k | −62% | |
| 255 | Suaman | Western North | district | 38k | −62% | |
| 256 | Builsa South | Upper East | district | 37k | −64% | |
| 257 | Birim South | Eastern | district | 36k | −65% | |
| 258 | Sekyere Afram Plains North | Ashanti | district | 33k | −68% | |
| 259 | Akatsi North | Volta | district | 33k | −68% | |
| 260 | Guan | Oti | district | 28k | −72% | |
| 261 | Banda | Bono | district | 28k | −72% |
district Official 2021 PHC count, redistributed by UNFPA as COD-PS on COD-AB boundaries. National total reconciles exactly to the published 30,832,019. Region and national figures are the published ADM1/ADM0 rows, not sums. Source: UNFPA / Ghana Statistical Service (COD-PS, 2021 Population and Housing Census), 2021.